description	diseaseOntologyId	link	name
A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.	DOID:635	http://purl.obolibrary.org/obo/DOID_635	acquired immunodeficiency syndrome
An encephalomyelitis characterized by inflammation located in brain and located in spinal cord that damages myelin. It usually occurs after viral infection, but also following vaccination, bacterial or parasitic infection.	DOID:639	http://purl.obolibrary.org/obo/DOID_639	acute disseminated encephalomyelitis
Progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. Cases of neonatal respiratory distress syndrome are not included in this definition.	C3353	http://purl.obolibrary.org/obo/NCIT_C3353	Acute Respiratory Distress Syndrome
An adrenal cortical hypofunction that is characterized by insufficient steroid hormone production by the adrenal glands.	DOID:13774	http://purl.obolibrary.org/obo/DOID_13774	Addison's disease
The process of change in the structure and function of an organism that occurs with the passage of time.	NCIT:C16269	http://purl.obolibrary.org/obo/NCIT_C16269	Aging
A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol. (UMLS CUI:C0001973)	DOID:0050741	http://purl.obolibrary.org/obo/DOID_0050741	alcohol dependence
A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.	DOID:1574	http://purl.obolibrary.org/obo/DOID_1574	alcohol use disorder
An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.	DOID:1205	http://purl.obolibrary.org/obo/DOID_1205	allergic hypersensitivity disease
A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.	DOID:4481	http://purl.obolibrary.org/obo/DOID_4481	allergic rhinitis
An autoimmune disease resulting in the loss of hair on the scalp and elsewhere on the body initially causing bald spots.	DOID:986	http://purl.obolibrary.org/obo/DOID_986	alopecia areata
A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.	DOID:10652	http://purl.obolibrary.org/obo/DOID_10652	Alzheimer's disease
A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.	DOID:2355	http://purl.obolibrary.org/obo/DOID_2355	anemia
Paroxysms of chest pain due to reduced oxygen to the heart. (UMLS CUI:C0002962)	NCIT:C51221	http://purl.obolibrary.org/obo/NCIT_C51221	Angina
A primary bacterial infectious disease that results_in infection located_in skin, located_in lung lymph nodes or located_in gastrointestinal tract, has_material_basis_in Bacillus anthracis, transmitted_by contact with infected animals or animal products, transmitted_by airborne spores or transmitted_by ingestion of undercooked meat from infected animals and has_symptom skin ulcer, has_symptom nausea, has_symptom poor appetite, has_symptom bloody diarrhea, has_symptom fever or has_symptom shortness of breath.	DOID:7427	http://purl.obolibrary.org/obo/DOID_7427	anthrax disease
An autoimmune disease that is characterized by recurrent venous or arterial thrombosis and/or fetal losses associated with characteristic elevated levels of antibodies directed against membrane anionic phospholipids (anticardiolipin).	DOID:2988	http://purl.obolibrary.org/obo/DOID_2988	antiphospholipid syndrome
An autoimmune disease that is characterized by myositis, arthralgia, Raynaud phenomenon, mechanic hands, interstitial lung disease, and serum autoantibodies to aminoacyl transfer RNA synthetases.	DOID:0080744	http://purl.obolibrary.org/obo/DOID_0080744	antisynthetase syndrome
A cognitive disorder that involves an excessive, irrational dread of everyday situations.	DOID:2030	http://purl.obolibrary.org/obo/DOID_2030	anxiety disorder
Arrhythmia is a cardiovascular system symptom consisting of an alteration in rhythm of the heartbeat either in time or force.	SYMP:0000287	http://purl.obolibrary.org/obo/SYMP_0000287	arrhythmia
A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has_symptom tachypnea and has_symptom cough. (UMLS CUI:C0032290)	DOID:0050152	http://purl.obolibrary.org/obo/DOID_0050152	aspiration pneumonia
A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.	DOID:2841	http://purl.obolibrary.org/obo/DOID_2841	asthma
An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking.	DOID:3310	http://purl.obolibrary.org/obo/DOID_3310	atopic dermatitis
A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain. (UMLS CUI:C0004238)	DOID:0060224	http://purl.obolibrary.org/obo/DOID_0060224	atrial fibrillation
An autoimmune disease of cardiovascular system that is characterized by deterioration of the function of the heart muscle.	DOID:0040095	http://purl.obolibrary.org/obo/DOID_0040095	autoimmune cardiomyopathy
An autoimmune hepatitis that is characterized by primary biliary cirrhosis clinical, biochemical, and histologic characteristics with antinuclear antibody positive sera.	DOID:0080742	http://purl.obolibrary.org/obo/DOID_0080742	autoimmune cholangitis
An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.	DOID:417	http://purl.obolibrary.org/obo/DOID_417	autoimmune disease
An autoimmune disease that is the abnormal functioning of the immune system resulting in production of antibodies or T cells against cells and/or tissues in the endocrine system.	DOID:0060005	http://purl.obolibrary.org/obo/DOID_0060005	autoimmune disease of endocrine system
An autoimmune disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the musculoskeletal system.	DOID:0060032	http://purl.obolibrary.org/obo/DOID_0060032	autoimmune disease of musculoskeletal system
An autoimmune disease of urogenital tract that is located_in the renal glomerulus.	DOID:0040094	http://purl.obolibrary.org/obo/DOID_0040094	autoimmune glomerulonephritis
An autoimmune disease of blood that is characterized by deficient red blood cells caused by auto-antibodies.	DOID:718	http://purl.obolibrary.org/obo/DOID_718	autoimmune hemolytic anemia
An autoimmune disease of gastrointestinal tract that results_in inflammation located_in liver caused by the body's immune system attacking the liver cells.	DOID:2048	http://purl.obolibrary.org/obo/DOID_2048	autoimmune hepatitis
An autoimmune disease of peripheral nervous system that results in peripheral neuropathy.	DOID:0040087	http://purl.obolibrary.org/obo/DOID_0040087	autoimmune peripheral neuropathy
A primary thrombocytopenia that involves relatively few platelets in blood as a result of autoantibodies.	DOID:8924	http://purl.obolibrary.org/obo/DOID_8924	autoimmune thrombocytopenic purpura
An influenza that results in infection located in respiratory tract of humans, domestic and wild birds, has_material_basis_in Influenza A virus, which is transmitted by contact with infected poultry. Five strains of avian influenza A viruses (H5N1, H7N3, H7N2, H7N7 and H9N2) are known to cause human infections. The infection has_symptom fever, has_symptom cough, has_symptom sore throat, has_symptom muscle aches, has_symptom nausea, has_symptom diarrhea, has_symptom vomiting, has_symptom neurologic changes, has_symptom pneumonia, and has_symptom acute respiratory distress.	DOID:4492	http://purl.obolibrary.org/obo/DOID_4492	avian influenza
Surgery performed in morbidly obese patients to help promote weight loss. The procedure aims at the reduction of the stomach size and it is usually achieved either with the implantation of a medical device or the removal of part of the stomach.	NCIT:C84399	http://purl.obolibrary.org/obo/NCIT_C84399	Bariatric Surgery
Bilateral pleural effusion (disorder) (UMLS CUI:C0747635)	SNOMEDCT:425802001	http://purl.bioontology.org/ontology/SNOMEDCT/425802001	Bilateral pleural effusion (disorder)
A cholestasis characterized by blockage of the ducts that carry bile from the liver to the gallbladder.	DOID:13608	http://purl.obolibrary.org/obo/DOID_13608	biliary atresia
A hematopoietic system disease that is characterized by abnormal blood clotting or bleeding.	DOID:1247	http://purl.obolibrary.org/obo/DOID_1247	blood coagulation disease
The injection of whole blood or a blood component directly into the bloodstream.	NCIT:C15192	http://purl.obolibrary.org/obo/NCIT_C15192	Blood Transfusion
A bone disease that results_in abnormal growth and development located_in bone or located_in cartilage.	DOID:0080006	http://purl.obolibrary.org/obo/DOID_0080006	bone development disease
A connective tissue disease that affects the structure or development of bone or causes an impairment of normal bone function.	DOID:0080001	http://purl.obolibrary.org/obo/DOID_0080001	bone disease
A brain glioma that has_material_basis_in abnormally proliferating cells derives_from glial cells, has_symptom seizure, headaches, nausea and vomiting, memory loss, changes to personality, mood or concentration; and localized neurological problems.	DOID:3073	http://purl.obolibrary.org/obo/DOID_3073	brain glioblastoma multiforme
A brain cancer that has_material_basis_in glial cells.	DOID:0060108	http://purl.obolibrary.org/obo/DOID_0060108	brain glioma
A thoracic cancer that originates in the mammary gland.	DOID:1612	http://purl.obolibrary.org/obo/DOID_1612	breast cancer
A bronchial disease that is a chronic inflammatory condition of one or more bronchi or bronchioles marked by dilatation and loss of elasticity of the walls resulting from damage to the airway wall leading to the formation of small sacs on the bronchial wall and impairment of cilia mobility in the lung. Inflammation of the bronchial wall increases mucus secretion which serves as a breeding ground for bacteria. Bronchiectasis is caused by repeated respiratory infections, immune deficiency disorders, hereditary disorders (cystic fibrosis or primary ciliary dyskinesia), mechanical factors (inhaled object or a lung tumor) or inhaling toxic substances. (UMLS CUI:C0006267)	DOID:9563	http://purl.obolibrary.org/obo/DOID_9563	bronchiectasis
A lung disease that is an inflammation of the bronchioles, the smallest air passages of the lungs. It is caused by viruses and bacteria. The disease has_symptom cough, has_symptom wheezing, has_symptom shortness of breath, has_symptom fever, has_symptom nasal flaring in infants and has_symptom bluish skin due to lack of oxygen.	DOID:2942	http://purl.obolibrary.org/obo/DOID_2942	bronchiolitis
A bronchial disease that is an inflammation of the bronchial tubes. It is caused by bacteria and viruses. The disease has_symptom cough with mucus, has_symptom shortness of breath, has_symptom low fever and has_symptom chest tightness.	DOID:6132	http://purl.obolibrary.org/obo/DOID_6132	bronchitis
Chronic lung disease requiring treatment with oxygen for at least 28 days and with a spectrum of severity from mild to severe, that predominantly affects premature infants. While the radiologic pattern is typical in the closer to term patient, the pattern in the small preterm infant is very non-discrete and variable.	NCIT:C90599	http://purl.obolibrary.org/obo/NCIT_C90599	Bronchopulmonary Dysplasia
A dermatitis that is characterized by blisters filled with a watery fluid, located_in skin. The disease is associated with the amount of gluten ingested.	DOID:8502	http://purl.obolibrary.org/obo/DOID_8502	bullous skin disease
A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.	DOID:162	http://purl.obolibrary.org/obo/DOID_162	cancer
A congestive heart failure characterized by a sudden stop in effective blood circulation due to the failure of the heart to contract effectively or at all.	DOID:0060319	http://purl.obolibrary.org/obo/DOID_0060319	cardiac arrest
A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.	DOID:0050700	http://purl.obolibrary.org/obo/DOID_0050700	cardiomyopathy
A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.	DOID:1287	http://purl.obolibrary.org/obo/DOID_1287	cardiovascular system disease
An autoimmune disease of gastrointestinal tract that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite.	DOID:10608	http://purl.obolibrary.org/obo/DOID_10608	celiac disease
A subperiosteal hemorrhage limited to the surface of one cranial bone, a usually benign condition seen in the newborn as a result of bone trauma.	NCIT:C50484	http://purl.obolibrary.org/obo/NCIT_C50484	Cephalohematoma
A brain disease that is caused by damage to the motor control centers of the developing brain during pregnancy, during childbirth or after birth, which affects muscle movement and balance.	DOID:1969	http://purl.obolibrary.org/obo/DOID_1969	cerebral palsy
An vascular disease that is characterized by dysfunction of the blood vessels supplying the brain.	DOID:6713	http://purl.obolibrary.org/obo/DOID_6713	cerebrovascular disease
A viral infectious disease that results_in infection located_in skin, has_material_basis_in Human herpesvirus 3, which is transmitted_by direct contact with secretions from the rash, or transmitted_by droplet spread of respiratory secretions. The infection has_symptom anorexia, has_symptom myalgia, has_symptom nausea, has_symptom fever, has_symptom headache, has_symptom sore throat, and has_symptom blisters.	DOID:8659	http://purl.obolibrary.org/obo/DOID_8659	chickenpox
A viral infectious disease that results_in infection located_in joint, has_material_basis_in Chikungunya virus, which is transmitted_by Aedes mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom maculopapular rash.	DOID:0050012	http://purl.obolibrary.org/obo/DOID_0050012	chikungunya
childhood type dermatomyositis	DOID:14203	http://purl.obolibrary.org/obo/DOID_14203	childhood type dermatomyositis
A commensal bacterial infectious disease that is caused by Chlamydia trachomatis.	DOID:11263	https://disease-ontology.org/?id=DOID:11263	chlamydia
choledochal cyst	DOID:899	http://purl.obolibrary.org/obo/DOID_899	choledochal cyst
A primary bacterial infectious disease that is described as an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae, which is characterized by profuse watery diarrhea, vomiting, leg cramps, circulatory collapse and shock.	DOID:1498	http://purl.obolibrary.org/obo/DOID_1498	cholera
A placenta disease that is an inflammation of the fetal membranes (amnion and chorion) due to a bacterial infection.	DOID:0050697	http://purl.obolibrary.org/obo/DOID_0050697	chorioamnionitis
A genetic disease that has_material_basis_in extra, missing, or re-arranged chromosomes.	DOID:0080014	http://purl.obolibrary.org/obo/DOID_0080014	chromosomal disease
A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, fall within abnormal homeostatic range.	OGMS:0000064	http://purl.obolibrary.org/obo/OGMS_0000064	chronic disease course
A syndrome of unknown etiology. Chronic fatigue syndrome (CFS) is a clinical diagnosis characterized by an unexplained persistent or relapsing chronic fatigue that is of at least six months' duration, is not the result of ongoing exertion, is not substantially alleviated by rest, and results in substantial reduction of previous levels of occupational, educational, social, or personal activities. Common concurrent symptoms of at least six months duration include impairment of memory or concentration, diffuse pain, sore throat, tender lymph nodes, headaches of a new type, pattern, or severity, and nonrestorative sleep. The etiology of CFS may be viral or immunologic. Neurasthenia and fibromyalgia may represent related disorders. Also known as myalgic encephalomyelitis.	NCIT_C3037	http://purl.obolibrary.org/obo/NCIT_C3037	Chronic Fatigue Syndrome
A kidney failure that is characterized by the gradual loss of kidney function. (UMLS CUI:C1561643)	DOID:784	http://purl.obolibrary.org/obo/DOID_784	chronic kidney disease
Hepatic necrosis, inflammation, or scarring due to any cause that persists for more than 6 months. Manifestations may include signs and symptoms of cholestasis, portal hypertension, and/or abnormal liver function tests. (UMLS CUI:C0341439)	NCIT:C113609	http://purl.obolibrary.org/obo/NCIT_C113609	Chronic Liver Disease
An obstructive lung disease that is characterized by irreversible airflow obstruction due to chronic bronchitis, emphysema, and/or small airways disease.	DOID:3083	http://purl.obolibrary.org/obo/DOID_3083	chronic obstructive pulmonary disease
Chronic plaque psoriasis is the most common presentation of psoriasis. It presents as small to large, well-demarcated, red, scaly and thickened areas of skin. It most likely to affect elbows, knees, and lower back but may arise on any part of the body.	N/A	https://dermnetnz.org/topics/chronic-plaque-psoriasis/	chronic plaque psoriasis
Inflammation of the paranasal sinuses that typically lasts beyond eight weeks. It is caused by infections, allergies, and the presence of sinus polyps or deviated septum. Signs and symptoms include headache, nasal discharge, swelling in the face, dizziness, and breathing difficulties. (UMLS CUI:C0149516)	NCIT:C35151	http://purl.obolibrary.org/obo/NCIT_C35151	Chronic Sinusitis
A chronic urticaria that is characterized by urticaria independent of any exogenous stimulus.	DOID:0080749	http://purl.obolibrary.org/obo/DOID_0080749	chronic spontaneous urticaria
liver cirrhosis	DOID:5082	http://purl.obolibrary.org/obo/DOID_5082	cirrhosis
A first neurologic episode caused by inflammation/demyelination of one or more central nervous system sites that lasts at least 24 hours. (SNOMEDCT_US)	UMLS CUI:C2921627	https://uts.nlm.nih.gov/uts/umls/concept/C2921627	clinically isolated syndrome
A colitis characterized by an overgrowth of Clostridium difficile bacteria.	DOID:0060185	http://purl.obolibrary.org/obo/DOID_0060185	Clostridium difficile colitis
An inflammatory bowel disease that involves inflammation located_in colon.	DOID:0060180	http://purl.obolibrary.org/obo/DOID_0060180	colitis
A large intestine cancer that is located_in the colon and/or located_in the rectum.	DOID:9256	http://purl.obolibrary.org/obo/DOID_9256	colorectal cancer
An agammaglobulinemia that is results in insufficient production of antibodies needed to respond to exposure of pathogens and is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells.	DOID:12177	http://purl.obolibrary.org/obo/DOID_12177	common variable immunodeficiency
An adrenal gland disease that is characterized by cortisol deficiency, hypoaldosteronism and excessive or insufficient sex hormones, has_material_basis_in the mutation in the gene for 21-hydroxylase, 11beta-hydroxylase, 3beta-hydroxysteroid, 17alpha-hydroxylase or 20,22-desmolase.	DOID:0050546	http://purl.obolibrary.org/obo/DOID_0050546	congenital adrenal insufficiency
congenital heart disease	DOID:1682	http://purl.obolibrary.org/obo/DOID_1682	congenital heart disease
A syphilis that results_in a multisystem infection in the fetus via the placenta.	DOID:9856	http://purl.obolibrary.org/obo/DOID_9856	congenital syphilis
A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.	DOID:6000	http://purl.obolibrary.org/obo/DOID_6000	congestive heart failure
A conjunctival disease characterized by an inflammation of the conjunctiva, the outermost layer of the eye and the inner surface of the eyelids.	DOID:6195	http://purl.obolibrary.org/obo/DOID_6195	conjunctivitis
A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage.	DOID:65	http://purl.obolibrary.org/obo/DOID_65	connective tissue disease
An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.	DOID:3393	http://purl.obolibrary.org/obo/DOID_3393	coronary artery disease
A Coronavirus infection that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2.	DOID:0080600	http://purl.obolibrary.org/obo/DOID_0080600	COVID-19
Acute respiratory distress syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	C171551	http://purl.obolibrary.org/obo/NCIT_C171551	COVID-19-Associated Acute Respiratory Distress Syndrome
A neuropathy that is located_in one of the twelve cranial nerves.	DOID:5656	http://purl.obolibrary.org/obo/DOID_5656	cranial nerve disease
A COVID-19 that is characterized by the criteria for acute respiratory distress syndrome (ARDS), sepsis, septic shock, or other conditions that would normally require the provision of life sustaining therapies such as mechanical ventilation (invasive or non-invasive) or vasopressor therapy. https://www.who.int/publications/i/item/WHO-2019-nCoV-clinical-2021-1	DOID:0081012	http://purl.obolibrary.org/obo/DOID_0081012	critical COVID-19
An intestinal disease that involves inflammation located_in intestine.	DOID:8778	http://purl.obolibrary.org/obo/DOID_8778	Crohn's disease
A lupus erythematosus that causes skin lesions on parts of the body that are exposed to sunlight.	DOID:0050169	http://purl.obolibrary.org/obo/DOID_0050169	cutaneous lupus erythematosus
A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.	DOID:1485	http://purl.obolibrary.org/obo/DOID_1485	cystic fibrosis
Polycystic kidney disease (PKD) is an inherited disorder in which clusters of cysts develop primarily within your kidneys, causing your kidneys to enlarge and lose function over time. Cysts are noncancerous round sacs containing fluid. The cysts vary in size, and they can grow very large.	DOID:2975	http://purl.obolibrary.org/obo/DOID_2975	cystic kidney disease
A lysosomal storage disease characterized by the abnormal accumulation of cystine in the lysosomes. It follows an autosomal recessive inheritance pattern and that has_material_basis_in mutations in the CTNS gene, located on chromosome 17.	DOID:1064	http://purl.obolibrary.org/obo/DOID_1064	cystinosis
Acute myeloid leukemia not associated with cytogenetic abnormalities.	NCIT:C122687	http://purl.obolibrary.org/obo/NCIT_C122687	Cytogenetically Normal Acute Myeloid Leukemia
A herpesvirus infection caused by Cytomegalovirus. Healthy individuals generally do not produce symptoms. However, the infection may be life-threatening in affected immunocompromised patients. The virus may cause retinitis, esophagitis, gastritis, and colitis. Morphologically, it is characterized by the presence of intranuclear inclusion bodies.	NCIT:C53649	http://purl.obolibrary.org/obo/NCIT_C53649	Cytomegaloviral Infection
A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior.	DOID:1307	http://purl.obolibrary.org/obo/DOID_1307	dementia
No definition yet. Semantic Types:Mental or Behavioral Dysfunction	UMLS CUI:C0543884	https://uts.nlm.nih.gov/uts/umls/concept/C0543884	Dementia with psychosis
A viral infectious disease that results in infection, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted by Aedes mosquito bite. The infection has symptom fever, has symptom severe headache, has symptom severe pain behind the eyes, has symptom joint pain, has symptom muscle and bone pain, has symptom rash, and has symptom mild bleeding.	DOID:12205	http://purl.obolibrary.org/obo/DOID_12205	dengue disease
A dengue disease that occurs when a person experiences a second infection with a heterologous Dengue virus serotype, which is transmitted_by Aedes mosquito bite. The infection has_symptom hemorrhagic lesions of the skin, has_symptom thrombocytopenia, has_symptom reduction in the fluid part of the blood, and has_symptom high fever.	DOID:12206	http://purl.obolibrary.org/obo/DOID_12206	dengue hemorrhagic fever
Dependence on peritoneal dialysis due to end stage renal disease (UMLS CUI:C1997877)	SNOMEDCT:428937001	http://purl.bioontology.org/ontology/SNOMEDCT/428937001	Dependence on peritoneal dialysis due to end stage renal disease
A myositis that results_in inflammation located_in muscle or located_in skin where a skin rash is often seen prior to the onset of muscle weakness. The disease may result from either a viral infection or an autoimmune reaction.	DOID:10223	http://purl.obolibrary.org/obo/DOID_10223	dermatomyositis
A cutaneous mycosis that results_in fungal infection located_in scalp, located_in glabrous skin, or located_in nail, has_material_basis_in Ascomycota fungi that belong to a group called dermatophytes, which have the ability to utilize keratin as a nutrient source.	DOID:8913	http://purl.obolibrary.org/obo/DOID_8913	dermatophytosis
A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development.	DOID:0060037	http://purl.obolibrary.org/obo/DOID_0060037	developmental disorder of mental health
A glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.	DOID:9351	http://purl.obolibrary.org/obo/DOID_9351	diabetes mellitus
A primary bacterial infectious disease that is characterized by sore throat, low fever, and an adherent membrane (a pseudomembrane) on the tonsils, pharynx, and/or nasal cavity. A milder form of diphtheria can be restricted to the skin. It is caused by Corynebacterium diphtheriae, an aerobic Gram-positive bacterium. Diphtheria toxin spreads through the bloodstream and can lead to potentially life-threatening complications that affect other organs of the body, such as the heart and kidneys.	DOID:11405	http://purl.obolibrary.org/obo/DOID_11405	diphtheria
A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.	DOID:4	http://purl.obolibrary.org/obo/DOID_4	disease
A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions.	DOID:0050117	http://purl.obolibrary.org/obo/DOID_0050117	disease by infectious agent
A disease that involving errors in metabolic processes of building or degradation of molecules.	DOID:0014667	http://purl.obolibrary.org/obo/DOID_0014667	disease of metabolism
An intestinal disease characterized by the formation and inflammation of diverticula within the bowel wall. (UMLS CUI:C0012813)	DOID:7475	http://purl.obolibrary.org/obo/DOID_7475	diverticulitis
Dyspnea experienced during minimal exertion.	NCIT_C191546	https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C191546	Dyspnea with Mild Physical Activity
Dyspnea experienced during moderate exertion.	NCIT_C191547	https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C191547	Dyspnea with Moderate Physical Activity
A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Zaire ebolavirus, has_material_basis_in Sudan ebolavirus, has_material_basis_in Cote d'Ivoire ebolavirus, or has_material_basis_in Bundibugyo ebolavirus, which are transmitted_by contact with the body fluids of an infected animal or person, transmitted by contaminated fomites, or transmitted by infected medical equipment. The infection has_symptom fever, has_symptom headache, has_symptom joint pain, has_symptom muscle aches, has_symptom sore throat, has_symptom weakness, has_symptom diarrhea, has_symptom vomiting, has_symptom stomach pain, has_symptom rash, has_symptom red eyes, has_symptom hiccups, and has_symptom internal and external bleeding.	DOID:4325	http://purl.obolibrary.org/obo/DOID_4325	Ebola hemorrhagic fever
An infection that is caused by Epstein-Barr virus.	NCIT:C38759	http://purl.obolibrary.org/obo/NCIT_C38759	EBV Infection
A lymphoproliferative disorder that develops following organ transplantation and is associated with Epstein-Barr virus infection.	NCIT:C27696	http://purl.obolibrary.org/obo/NCIT_C27696	EBV-Related Post-Transplant Lymphoproliferative Disorder
A herpes simplex that results_in infection located_in skin, effected by preexisting dermatosis, has_material_basis_in Human herpesvirus 1 or Human herpesvirus 2. The infection has_symptom watery blisters, has_symptom fever, and has_symptom swelling of the lymph nodes.	DOID:9123	http://purl.obolibrary.org/obo/DOID_9123	eczema herpeticum
ICD10CM:T88.1 (can ref: https://academic.oup.com/cid/article-abstract/54/6/832/290140)	UMLS CUI:C0936249	https://uts.nlm.nih.gov/uts/umls/concept/C0936249	eczema vaccinatum
A food allergy that is an allergy or hypersensitivity to dietary substances from the yolk or whites of eggs, causing an overreaction of the immune system which may lead to severe physical symptoms.	DOID:4377	http://purl.obolibrary.org/obo/DOID_4377	egg allergy
A brain disease that is characterized as an acute inflammation of the brain with flu-like symptoms.	DOID:9588	http://purl.obolibrary.org/obo/DOID_9588	encephalitis
A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.	DOID:783	http://purl.obolibrary.org/obo/DOID_783	end stage renal disease
A endocardium disease characterized by inflammation of the endocardium of the heart chambers and valves.	DOID:10314	http://purl.obolibrary.org/obo/DOID_10314	endocarditis
An esophagitis characterized by inflammation involving eosinophils located_in esophagus.	DOID:13922	http://purl.obolibrary.org/obo/DOID_13922	eosinophilic esophagitis
A vesiculobullous skin disease that is characterized by formation of blisters with only minor skin trauma, which can cause widespread wounds, dehydration, electrolyte abnormalities, and severe infection, frequently develops_from mutations in connective tissue elements, including genes encoding keratin, collagen, and laminin.	DOID:2730	http://purl.obolibrary.org/obo/DOID_2730	epidermolysis bullosa
A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.	DOID:1826	http://purl.obolibrary.org/obo/DOID_1826	epilepsy
Infection with the organism Escherichia Coli.	NCIT:C34594	http://purl.obolibrary.org/obo/NCIT_C34594	Escherichia Coli Infection
esophageal atresia	DOID:10485	http://purl.obolibrary.org/obo/DOID_10485	esophageal atresia
A gastrointestinal system disease that is characterized by abnormal development of the esophagus and trachea where the upper esophagus does not connect (atresia) to the lower esophagus and stomach and may also include tracheoesophageal fistula where the esophagus and the trachea are abnormally connected which allows fluids from the esophagus to get into the airways and interfere with breathing.	DOID:0080171	http://purl.obolibrary.org/obo/DOID_0080171	esophageal atresia/tracheoesophageal fistula
A clinical finding indicating less than normal growth in an infant or child, or a state of global decline in an adult. (UMLS CUI:C0015544)	NCIT:C107587	http://purl.obolibrary.org/obo/NCIT_C107587	Failure to Thrive
A record of a patient's background regarding health and disease events of blood relatives. A patient's family medical history may be important in diagnosing existing conditions.	NCIT:C17726	http://purl.obolibrary.org/obo/NCIT_C17726	Family Medical History
fibromyalgia	DOID:631	http://purl.obolibrary.org/obo/DOID_631	fibromyalgia
Focal segmental glomerulosclerosis (FSGS) is a disease in which scar tissue develops on the parts of the kidneys that filter waste from the blood (glomeruli). FSGS can be caused by a variety of conditions.	DOID:1312	http://purl.obolibrary.org/obo/DOID_1312	focal segmental glomerulosclerosis
A hypersensitivity reaction type I disease that is an abnormal response to a food, triggered by the body's immune system.	DOID:3044	http://purl.obolibrary.org/obo/DOID_3044	food allergy
gastroesophageal reflux disease	DOID:8534	http://purl.obolibrary.org/obo/DOID_8534	gastroesophageal reflux disease
A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.	DOID:3068	http://purl.obolibrary.org/obo/DOID_3068	glioblastoma
An autoimmune disease that is characterized by antibody attack of the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure.	DOID:9808	http://purl.obolibrary.org/obo/DOID_9808	Goodpasture syndrome
An autoimmune disease that is characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract, glomerulonephritis, vasculitis, and the presence of antineutrophil cytoplasmatic autoantibodies (ANCAs) in patient sera, and is located_in lung, located_in kidney, located_in skin resulting from an autoimmune attack by antineutrophil cytoplasmic antibodies against small and medium-size blood vessels.	DOID:12132	http://purl.obolibrary.org/obo/DOID_12132	granulomatosis with polyangiitis
An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.	DOID:12361	http://purl.obolibrary.org/obo/DOID_12361	Graves' disease
An autoimmune disease of peripheral nervous system that causes body's immune system to attack part of the peripheral nervous system.	DOID:12842	http://purl.obolibrary.org/obo/DOID_12842	Guillain-Barre syndrome
A bacterial meningitis that has_material_basis_in Haemophilus influenzae infection.	DOID:0080179	http://purl.obolibrary.org/obo/DOID_0080179	haemophilus meningitis
Having no significant health-related issues.	NCIT:C115935	http://purl.obolibrary.org/obo/NCIT_C115935	healthy
Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction. (UMLS CUI:C0018801)	NCIT:C50577	http://purl.obolibrary.org/obo/NCIT_C50577	Heart Failure
A surgical procedure in which a damaged heart is removed and replaced by another heart from a suitable donor.	NCIT:C15246	http://purl.obolibrary.org/obo/NCIT_C15246	Heart Transplantation
A bacterial infection of the stomach, caused by Helicobacter pylori.  It is associated with the development of peptic ulcer and mucosa-associated lymphoid tissue lymphoma.	NCIT:C39293	http://purl.obolibrary.org/obo/NCIT_C39293	Helicobacter Pylori Infection
An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.	DOID:2531	http://purl.obolibrary.org/obo/DOID_2531	hematologic cancer
An individual receiving a hematopoietic cell transplant	CL507993	https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncim/CL507993	Hematopoietic Cell Transplant Recipient
A disease of anatomical entity that has_material_basis_in hematopoietic cells.	DOID:74	http://purl.obolibrary.org/obo/DOID_74	hematopoietic system disease
A central nervous system disease that is characterized by the complete paralysis of half of the body.	DOID:10969	http://purl.obolibrary.org/obo/DOID_10969	hemiplegia
hemoglobinopathy	DOID:2860	http://purl.obolibrary.org/obo/DOID_2860	hemoglobinopathy
A kidney disease that is characterized by hemolytic anemia, thrombocytopenia, and renal failure caused by platelet thrombi in the microcirculation of the kidney and other organs.	DOID:12554	http://purl.obolibrary.org/obo/DOID_12554	hemolytic-uremic syndrome
(UMLS CUI:C0267797)	DOID:2237	http://purl.obolibrary.org/obo/DOID_2237	hepatitis
A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis A virus, which is transmitted_by ingestion of contaminated food or water, or transmitted_by direct contact with an infected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.	DOID:12549	http://purl.obolibrary.org/obo/DOID_12549	hepatitis A
A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus, which is transmitted_by sexual contact, transmitted_by blood transfusions, and transmitted_by fomites like needles or syringes. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.	DOID:2043	http://purl.obolibrary.org/obo/DOID_2043	hepatitis B
A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis C virus, which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.	DOID:1883	http://purl.obolibrary.org/obo/DOID_1883	hepatitis C
A viral infectious disease that results_in infection located_in nerve fiber, has_material_basis_in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The virus is transmitted_by direct contact with the rash, which can develop into chickenpox in newly-infected individuals. The infection has_symptom rash which is followed by blisters, has_symptom headache, has_symptom fever, has_symptom malaise, has_symptom itching, has_symptom burning pain, and has_symptom paresthesia.	DOID:8536	http://purl.obolibrary.org/obo/DOID_8536	herpes zoster
A viral infectious disease that has_material_basis_in Human betaherpesvirus 5.	DOID:0080827	http://purl.obolibrary.org/obo/DOID_0080827	human cytomegalovirus infection
A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.	DOID:526	http://purl.obolibrary.org/obo/DOID_526	human immunodeficiency virus infectious disease
hydronephrosis	DOID:11111	http://purl.obolibrary.org/obo/DOID_11111	hydronephrosis
An artery disease characterized by chronic elevated blood pressure in the arteries.	DOID:10763	http://purl.obolibrary.org/obo/DOID_10763	hypertension
No definition yet. Semantic Types:Disease or Syndrome	UMLS CUI:C0857354	https://uts.nlm.nih.gov/uts/umls/concept/C0857354	Hypertension not adequately controlled
A glucose metabolism disease that is characterized by abnormally low levels of blood glucose.	DOID:9993	http://purl.obolibrary.org/obo/DOID_9993	hypoglycemia
Lower than normal levels of sodium in the circulating blood. (UMLS CUI:C0020625)	NCIT:C37976	http://purl.obolibrary.org/obo/NCIT_C37976	Hyponatremia
A thyroid gland disease which involves an underproduction of thyroid hormone.	DOID:1459	http://purl.obolibrary.org/obo/DOID_1459	hypothyroidism
A gynecologic surgery history in which a woman has had a hysterectomy.	OBI:0002398	http://purl.obolibrary.org/obo/OBI_0002398	hysterectomy history
A skin disease characterized by drying and scaling of skin with the accumulation of thick scales and cracks that may be painful or bleed.	DOID:1697	http://purl.obolibrary.org/obo/DOID_1697	ichthyosis
A pulmonary fibrosis that is characterized by scarring of the lung.	DOID:0050156	http://purl.obolibrary.org/obo/DOID_0050156	idiopathic pulmonary fibrosis
A loss of any arm of immune functions, resulting in potential or actual increase in infections. This state may be reached secondary to specific genetic lesions, syndromes with unidentified or polygenic causes, acquired deficits from other disease states, or as result of therapy for other diseases or conditions. (UMLS CUI:C2186379)	NCIT:C14139	http://purl.obolibrary.org/obo/NCIT_C14139	Immunocompromised
An innate tolerance that prevents the body from attacking native proteins and tissue.	NCIT:C17712	http://purl.obolibrary.org/obo/NCIT_C17712	Immunologic Tolerance
Immunosuppressive Disorder A disorder in which immune function is suppressed.	C178942	http://purl.obolibrary.org/obo/NCIT_C178942	Immunosuppressive Disorder
An intestinal disease characterized by inflammation located in all parts of digestive tract.	DOID:0050589	http://purl.obolibrary.org/obo/DOID_0050589	inflammatory bowel disease
An infectious or non infectious disorder characterized by signs and symptoms derived from focal or extensive tissue infiltration by acute (e.g., polymorphonuclear) or chronic (e.g., lymphocytic-plasmacytic) inflammatory cells. Representative examples of infectious disorders include viral infections, bacterial infections, and parasitic infections. Representative examples of non-infectious inflammatory disorders include inflammatory bowel disease and inflammatory polyps	C93210	http://purl.obolibrary.org/obo/NCIT_C93210	Inflammatory Disorder
A viral infectious disease that results in infection, located in respiratory tract, has_material_basis_in Influenzavirus A, has_material_basis_in Influenzavirus B, or has_material_basis_in Influenzavirus C, which are transmitted_by droplet spread of oronasal secretions during coughing, sneezing, or talking from an infected person. It is a highly contagious disease that affects birds and mammals and has_symptom chills, has_symptom fever, has_symptom sore throat, has_symptom runny nose, has_symptom muscle pains, has_symptom severe headache, has_symptom cough, and has_symptom weakness.	DOID:8469	http://purl.obolibrary.org/obo/DOID_8469	influenza
A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.	DOID:3082	http://purl.obolibrary.org/obo/DOID_3082	interstitial lung disease
Interstitial nephritis is a kidney disorder. The kidneys filter waste and extra fluid from the body. When you have interstitial nephritis, the spaces between tubules (small tubes) inside the kidney become inflamed. This reduces the kidneys' ability to filter properly.	DOID:1063	http://purl.obolibrary.org/obo/DOID_1063	interstitial nephritis
An intestinal disease that involves intestinal infection that has_material_basis_in viruses, bacteria, fungi and parasites.	DOID:100	http://purl.obolibrary.org/obo/DOID_100	intestinal infectious disease
Irritable bowel syndrome with diarrhea (UMLS CUI:C0348898)	SNOMEDCT:197125005	http://purl.bioontology.org/ontology/SNOMEDCT/197125005	Irritable bowel syndrome with diarrhea
A rheumatoid arthritis that involves an autoimmune disease onset in children under 16 which attacks the healthy cells and tissue of located_in joint.	DOID:676	http://purl.obolibrary.org/obo/DOID_676	juvenile rheumatoid arthritis
Dryness of the eye related to deficiency of the tear film components (aqueous, mucin, or lipid), lid surface abnormalities, or epithelial abnormalities. Keratoconjunctivitis sicca often results in a scratchy or sandy sensation (foreign body sensation) in the eyes, and may also be associated with itching, inability to produce tears, photosensitivity, redness, pain, and difficulty in moving the eyelids.	DOID:12895	http://purl.obolibrary.org/obo/DOID_12895	keratoconjunctivitis sicca
A kidney cortex disease that is characterized by death of the tissue in the outer part of the kidney that results from blockage of the small arteries that supply blood to the cortex and that causes acute kidney injury.	DOID:2973	http://purl.obolibrary.org/obo/DOID_2973	kidney cortex necrosis
A urinary system disease that is located in the kidney.	DOID:557	http://purl.obolibrary.org/obo/DOID_557	kidney disease
A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood.	DOID:1074	http://purl.obolibrary.org/obo/DOID_1074	kidney failure
The transfer of a healthy kidney from a donor to a patient for the purpose of replacing one of the failing kidneys of the patient.	NCIT:C15265	http://purl.obolibrary.org/obo/NCIT_C15265	Kidney Transplantation
A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal.	DOID:0050214	http://purl.obolibrary.org/obo/DOID_0050214	Lambert-Eaton myasthenic syndrome
A laryngeal disease that is characterized by inward collapse of flaccid supraglottic structures during inspiration. The most common symptom is noisy breathing (stridor) that is often worse when the infant is on his/her back or crying.	DOID:0080833	http://purl.obolibrary.org/obo/DOID_0080833	laryngomalacia
A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.	DOID:1240	http://purl.obolibrary.org/obo/DOID_1240	leukemia
A lichen disease that is located_in skin, located_in tongue or located_in oral mucosa, which presents itself in the form of papules, lesions or rashes.	DOID:9201	http://purl.obolibrary.org/obo/DOID_9201	lichen planus
A bacterial meningitis that has_material_basis_in Listeria monocytogenes infection.	DOID:11572	http://purl.obolibrary.org/obo/DOID_11572	Listeria meningitis
A hepatobiliary system cancer that is located_in the liver.	DOID:3571	http://purl.obolibrary.org/obo/DOID_3571	liver cancer
liver disease	DOID:409	http://purl.obolibrary.org/obo/DOID_409	liver disease
The transfer of a healthy liver allograft from a donor to a patient.	NCIT:C15271	http://purl.obolibrary.org/obo/NCIT_C15271	Liver Transplantation
localized scleroderma	DOID:8472	http://purl.obolibrary.org/obo/DOID_8472	localized scleroderma
A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.	DOID:3910	http://purl.obolibrary.org/obo/DOID_3910	lung adenocarcinoma
A respiratory system cancer that is located_in the lung.	DOID:1324	http://purl.obolibrary.org/obo/DOID_1324	lung cancer
A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.	DOID:850	http://purl.obolibrary.org/obo/DOID_850	lung disease
The surgical transfer of one or both lungs from one individual to another.	NCIT:C15274	http://purl.obolibrary.org/obo/NCIT_C15274	Lung Transplantation
An autoimmune disease that is characterized by a constellation of findings that include elevated antibodies to nuclear antigens, antiphospholipids, low complement levels, ulcers, non-scarring alopecia, renal or neurologic damage, and low white blood cell and platelet counts, has_symptom rashes, fatigue, arthritis, hair loss, seizures, and symptoms related to affected organs. (UMLS CUI:C0409974)	DOID:8857	http://purl.obolibrary.org/obo/DOID_8857	lupus erythematosus
A glomerulonephritis that is characterized by inflammation of the kidneys resulting from systemic lupus erythematosus.	DOID:0080162	http://purl.obolibrary.org/obo/DOID_0080162	lupus nephritis
A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia burgdorferi, which is transmitted_by blacklegged tick (Ixodes scapularis) or transmitted_by western blacklegged tick (Ixodes pacificus). The infection has_symptom fever, has_symptom headache, has_symptom fatigue, and has_symptom skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system.	DOID:11729	http://purl.obolibrary.org/obo/DOID_11729	Lyme disease
A viral infectious disease that results in infection located in brain, or located in meninges, or located in brain and meninges, has_material_basis_in Lymphocytic choriomeningitis virus, which is transmitted by common house mouse, Mus musculus. The infection has symptom fever, has symptom lack of appetite, has symptom headache, has symptom muscle aches, has symptom malaise, has symptom nausea, and has symptom vomiting.	DOID:12155	http://purl.obolibrary.org/obo/DOID_12155	lymphocytic choriomeningitis
A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs.	DOID:0060058	http://purl.obolibrary.org/obo/DOID_0060058	lymphoma
A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.	DOID:12365	http://purl.obolibrary.org/obo/DOID_12365	malaria
A primary or metastatic malignant neoplasm involving the stomach. (UMLS CUI:C0024623)	NCIT:C9331	http://purl.obolibrary.org/obo/NCIT_C9331	Malignant Gastric Neoplasm
A primary or metastatic malignant neoplasm involving the lung. (UMLS CUI:C0242379)	NCIT:C7377	http://purl.obolibrary.org/obo/NCIT_C7377	Malignant Lung Neoplasm
A viral infectious disease that results_in infection located_in skin, has_material_basis_in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection has_symptom fever, has_symptom cough, has_symptom coryza, has_symptom conjunctivitis, and has_symptom maculopapular, erythematous rash.	DOID:8622	http://purl.obolibrary.org/obo/DOID_8622	measles
A central nervous system disease that is characterized by an inflammation of the pia-arachnoid meninges. It can be caused by growth of bacteria, fungi, or parasites within the subarachnoid space or by the growth of bacteria or viruses within the meningeal or ependymal cells.	DOID:9471	http://purl.obolibrary.org/obo/DOID_9471	meningitis
A bacterial meningitis that has_material_basis_in Neisseria meningitidis infection.	DOID:0080176	http://purl.obolibrary.org/obo/DOID_0080176	meningococcal meningitis
A central nervous system disease that involves encephalitis which occurs along with meningitis.	DOID:10554	http://purl.obolibrary.org/obo/DOID_10554	meningoencephalitis
mental depression	DOID:1596	http://purl.obolibrary.org/obo/DOID_1596	mental depression
Middle East respiratory syndrome coronavirus	SNOMEDCT:697932005	http://purl.bioontology.org/ontology/SNOMEDCT/697932005	MERS-CoV
A combination of medical conditions that when present, increase the risk of heart attack, stroke, and diabetes mellitus. It includes the following medical conditions: increased blood pressure, central obesity, dyslipidemia, impaired glucose tolerance, and insulin resistance.	NCIT:C84442	http://purl.obolibrary.org/obo/NCIT_C84442	Metabolic Syndrome
A food allergy that results in adverse immune reaction to one or more of the proteins in cow's milk and/or the milk of other animals, which are normally harmless to the non-allergic individual.	DOID:4376	http://purl.obolibrary.org/obo/DOID_4376	milk allergy
Miscarriage is a reproductive system symptom characterized by the spontaneous expulsion of a human fetus before it is viable and especially between the 12th and 28th weeks of gestation.	SYMP:0000198	http://purl.obolibrary.org/obo/SYMP_0000198	miscarriage
(UMLS CUI:C0026266)	DOID:11502	http://purl.obolibrary.org/obo/DOID_11502	mitral valve insufficiency
A collagen disease that is considered an overlap of three diseases, systemic lupus erythematosus, scleroderma, and polymyositis with very high titers of circulating antinuclear antibody to a ribonucleoprotein antigen.	DOID:3492	http://purl.obolibrary.org/obo/DOID_3492	mixed connective tissue disease
A viral infectious disease that results_in infection located_in skin, has_material_basis_in Molluscum contagiosum virus, which is transmitted_by contact with the skin, and transmitted_by fomites. The infection has_symptom lesions which are flesh-colored with a pit in the center.	DOID:8867	http://purl.obolibrary.org/obo/DOID_8867	molluscum contagiosum
A myeloid neoplasm that is located_in the plasma cells in bone marrow. (UMLS CUI:C0026764)	DOID:9538	http://purl.obolibrary.org/obo/DOID_9538	multiple myeloma
Multiple, small, round or oval, benign or malignant growths in the lung(s), which can be due to infectious, inflammatory, or neoplastic processes. (UMLS CUI:C0748164)	NCIT:C122408	http://purl.obolibrary.org/obo/NCIT_C122408	Multiple Pulmonary Nodules
A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.	DOID:2377	http://purl.obolibrary.org/obo/DOID_2377	multiple sclerosis
A viral infectious disease that results in inflammation located in salivary gland, has_material_basis_in Mumps rubulavirus, which is transmitted by droplet spread of saliva or mucus from the mouth, nose, or throat of an infected person, or transmitted by contaminated fomites. The infection has symptom fever, has symptom headache, has symptom muscle aches, has symptom tiredness, has symptom loss of appetite, has symptom swollen and tender salivary glands under the ears or jaw on one or both sides of the face.	DOID:10264	http://purl.obolibrary.org/obo/DOID_10264	mumps
Muscle Invasive Bladder Carcinoma. A carcinoma that arises from the bladder mucosa and invades the muscle of the bladder wall.(NCI)	UMLS CUI:C4725841	https://uts.nlm.nih.gov/uts/umls/concept/C4725841	muscle invasive bladder cancer
A myopathy is characterized by progressive skeletal muscle weakness degeneration.	DOID:9884	http://purl.obolibrary.org/obo/DOID_9884	muscular dystrophy
A disease of anatomical entity that occurs in the muscular and/or skeletal system.	DOID:17	http://purl.obolibrary.org/obo/DOID_17	musculoskeletal system disease
An autoimmune disease of the nervous system that has_material_basis_in antibodies to acetylcholine receptors at the neuromuscular junction, has_symptom ptosis, has_symptom diplopia, has_symptom dysphagia, has_symptom dysarthria, has_symptom muscle weakness and has_symptom shortness of breath.	DOID:437	http://purl.obolibrary.org/obo/DOID_437	myasthenia gravis
A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.	DOID:5844	http://purl.obolibrary.org/obo/DOID_5844	myocardial infarction
An extrinsic cardiomyopathy that is characterized as an inflammation of the heart muscle.	DOID:820	http://purl.obolibrary.org/obo/DOID_820	myocarditis
A sleep disorder that involves an excessive urge to sleep at inappropriate times, such as while at work.	DOID:8986	http://purl.obolibrary.org/obo/DOID_8986	narcolepsy
A candidiasis that involves fungal infection in neonates caused by Candida species. Low birthweight and age, prolonged intravascular catheterization and the use of antibiotic drugs are the principle predisposing conditions for systemic candidiasis in neonates.	DOID:9577	http://purl.obolibrary.org/obo/DOID_9577	neonatal candidiasis
Injury to the central nervous system in the newborn period that occurs when there is insufficient delivery of oxygen to all or part of the brain.	NCIT:C119751	http://purl.obolibrary.org/obo/NCIT_C119751	Neonatal Hypoxic Ischemic Encephalopathy
A disposition inhering in a tumour by virtue of the bearer's disposition to spread and invade distant tissues.	PATO:0002098	http://purl.obolibrary.org/obo/PATO_0002098	neoplastic, metastatic
A kidney disease characterized by the formation of stoney concentrations in the kidneys.	DOID:585	http://purl.obolibrary.org/obo/DOID_585	nephrolithiasis
Nephrostomy tube (physical object) (UMLS CUI:C0184149)	SNOMEDCT:286628000	http://purl.bioontology.org/ontology/SNOMEDCT/286628000	Nephrostomy tube (physical object)
A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.	DOID:1184	http://purl.obolibrary.org/obo/DOID_1184	nephrotic syndrome
A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system.	DOID:863	http://purl.obolibrary.org/obo/DOID_863	nervous system disease
A neurofibromatosis classically characterized by cafe-au-lait spots, Lisch nodules in the eye, and fibromatous tumors of the skin or in some cases by a high load of spinal tumors that has_material_basis_in heterozygous mutation in NF1 on 17q11.2.	DOID:0111253	http://purl.obolibrary.org/obo/DOID_0111253	neurofibromatosis 1
No definition yet. Semantic Types:Disease or Syndrome	UMLS CUI:C2359473	https://uts.nlm.nih.gov/uts/umls/concept/C2359473	Neurological diseases or conditions
A neuropathy that affect the nerves that control the voluntary muscles. (UMLS CUI:C0027868)	DOID:440	http://purl.obolibrary.org/obo/DOID_440	neuromuscular disease
A central nervous system disease characterized by inflammation of the optic nerve (optic neuritis) and inflammation of the spinal cord (myelitis).	DOID:8869	http://purl.obolibrary.org/obo/DOID_8869	neuromyelitis optica
A viral infectious disease that results_in infection in birds and humans, has_material_basis_in Newcastle disease virus, which is transmitted_by contact with feces and urine of an infected bird, or transmitted_by fomites. The infection has_symptom conjunctivitis, has_symptom headache, and has_symptom lacrimation in humans, and has_symptom gasping, has_symptom coughing, has_symptom twisting of head and neck, has_symptom circling, has_symptom complete paralysis, has_symptom watery diarrhea, and has_symptom reduced egg production in birds.	DOID:2929	http://purl.obolibrary.org/obo/DOID_2929	Newcastle disease
A COVID-19 that is characterized by the absence of any criteria for severe or critical COVID-19. https://www.who.int/publications/i/item/WHO-2019-nCoV-clinical-2021-1	DOID:0081014	http://purl.obolibrary.org/obo/DOID_0081014	non-severe COVID-19
Determination of a value is not relevant in the current context	NCIT_C48660	http://purl.obolibrary.org/obo/NCIT_C48660	Not Applicable
Not stated explicitly or in detail	NCIT_C38046	http://purl.obolibrary.org/obo/NCIT_C38046	Not Specified
A nutrition disease that is characterized by deficiency of a nutritional element, such as a vitamin, mineral, carbohydrate, protein, fat, or general energy content.	DOID:5113	http://purl.obolibrary.org/obo/DOID_5113	nutritional deficiency disease
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.	DOID:9970	http://purl.obolibrary.org/obo/DOID_9970	obesity
optic nerve glioma	DOID:4992	http://purl.obolibrary.org/obo/DOID_4992	optic nerve glioma
An optic nerve disease that results_in inflammation located_in optic nerve which may cause a complete or partial loss of vision.	DOID:1210	http://purl.obolibrary.org/obo/DOID_1210	optic neuritis
An arthritis that has_material_basis_in worn out cartilage located_in joint.	DOID:8398	http://purl.obolibrary.org/obo/DOID_8398	osteoarthritis
The surgical transfer of a pancreas from one individual to another.	NCIT:C15293	http://purl.obolibrary.org/obo/NCIT_C15293	Pancreas Transplantation
An endocrine gland cancer located_in the pancreas. (UMLS CUI:C0235974)	DOID:1793	http://purl.obolibrary.org/obo/DOID_1793	pancreatic cancer
The surgical transfer of pancreatic islet cells from one individual to another.	NCIT:C15352	http://purl.obolibrary.org/obo/NCIT_C15352	Pancreatic Islet Transplantation
A skin disease that is characterized by inflammation of subcutaneous adipose tissue.	DOID:1526	http://purl.obolibrary.org/obo/DOID_1526	panniculitis
paraplegia	DOID:607	http://purl.obolibrary.org/obo/DOID_607	paraplegia
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.	DOID:14330	http://purl.obolibrary.org/obo/DOID_14330	Parkinson's disease
Surgical removal of part of the small intestine. (UMLS CUI:C0192616)	NCIT:C51512	http://purl.obolibrary.org/obo/NCIT_C51512	Partial Small Intestine Resection
A legume allergy that is an allergy or hypersensitivity to dietary substances from peanuts causing an overreaction of the immune system which in a small percentage of people may lead to severe physical symptoms.	DOID:4378	http://purl.obolibrary.org/obo/DOID_4378	peanut allergy
PANS pediatric acute-onset neuropsychiatric syndrome	C000631768	http://purl.bioontology.org/ontology/MESH/C000631768	Pediatric acute-onset neuropsychiatric syndrome
A pemphigus characterized by autosomal dominant blisters and erosions on the skin and mucous membranes erosions cause by autoantibodies to intercellular cement substance.	DOID:0060851	http://purl.obolibrary.org/obo/DOID_0060851	pemphigus vulgaris
peptic ulcer disease	DOID:750	http://purl.obolibrary.org/obo/DOID_750	peptic ulcer disease
Allergic rhinitis caused by indoor allergens and lasting year round.	NCIT:C92189	http://purl.obolibrary.org/obo/NCIT_C92189	Perennial Allergic Rhinitis
perinatal necrotizing enterocolitis	DOID:8677	http://purl.obolibrary.org/obo/DOID_8677	perinatal necrotizing enterocolitis
A vascular disease that is characterized by obstruction of larger arteries not within the coronary, aortic arch vasculature, or brain.	DOID:341	http://purl.obolibrary.org/obo/DOID_341	peripheral vascular disease
A form of dialysis that uses the peritoneum as a membrane across which the infused diasylate exchanges nutrients for waste products that are removed when the fluid is exchanged. (UMLS CUI:C0031139)	NCIT:C15297	http://purl.obolibrary.org/obo/NCIT_C15297	Peritoneal Dialysis
A nutritional deficiency disease that is characterized by a decrease in red blood cells due to malabsorption of vitamin B12, has_symptom fatigue, pallor, shortness of breath, glossitis, ataxia, and/or paresthesia, has_material_basis_in atrophic gastritis, autoimmune disorder affecting the production or function of intrinsic factor, and/or genetic factors.	DOID:13381	http://purl.obolibrary.org/obo/DOID_13381	pernicious anemia
A commensal bacterial infectious disease that results_in inflammation located_in respiratory tract, has_material_basis_in Bordetella pertussis, or has_material_basis_in Bordetella parapertussis, which produce toxins that paralyze the cilia of the respiratory epithelial cells. The infection is characterized by a prolonged, high-pitched, deeply indrawn breath (whoop).	DOID:1116	http://purl.obolibrary.org/obo/DOID_1116	pertussis
A developmental disorder of mental health that refers to a group of five disorders characterized by impairments in socialization and communication, as well as restricted interests and repetitive behaviors.	DOID:0060040	http://purl.obolibrary.org/obo/DOID_0060040	pervasive developmental disorder
An upper respiratory tract disease involving inflammation of the throat or pharynx resulting from bacterial, viral, fungal infections or irritants like pollutants or chemical substances and smoking. The infection is often referred to as sore throat. The symptoms include pain during swallowing, enlarged tonsils coated with a white discharge, runny nose, cough and slight fever.	DOID:2275	http://purl.obolibrary.org/obo/DOID_2275	pharyngitis
A disease that has_material_basis_in a genetic abnormality, error with embryonic development, infection or compromised intrauterine environment.	DOID:0080015	http://purl.obolibrary.org/obo/DOID_0080015	physical disorder
An endocrine system disease that is located_in the pituitary gland.	DOID:53	http://purl.obolibrary.org/obo/DOID_53	pituitary gland disease
A uterine disease that is located_in the placenta.	DOID:780	http://purl.obolibrary.org/obo/DOID_780	placenta disease
A primary bacterial infectious disease that results_in infection, located_in lymph node, located_in vasculature or located_in lungs, has_material_basis_in Yersinia pestis, which is transmitted_by oriental rat flea (Xenopsylla cheopis) infected by feeding on rodents and other mammals, transmitted_by air, transmitted_by direct contact or transmitted_by ingestion of contaminated undercooked food.	DOID:3482	http://purl.obolibrary.org/obo/DOID_3482	plague
A malaria described as a severe form of the disease caused by a parasite Plasmodium falciparum, which is marked by irrregular recurrence of paroxysms and prolonged or continuous fever.	DOID:14067	http://purl.obolibrary.org/obo/DOID_14067	Plasmodium falciparum malaria
A malaria that is caused by the protozoan parasite Plasmodium vivax, which induces paroxysms at 48-hour intervals.	DOID:12978	http://purl.obolibrary.org/obo/DOID_12978	Plasmodium vivax malaria
No definition yet. Semantic Types:Disease or Syndrome	UMLS CUI:C0747636	https://uts.nlm.nih.gov/uts/umls/concept/C0747636	Pleural effusions, chronic
A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation).	DOID:552	http://purl.obolibrary.org/obo/DOID_552	pneumonia
A collagen disease that is characterized by pain, stiffness, and tenderness of the proximal muscle groups including the shoulder, pelvic girdle and the neck.	DOID:853	http://purl.obolibrary.org/obo/DOID_853	polymyalgia rheumatica
A myositis that is characterized by muscle weakness affecting both sides of your body.	DOID:0080745	http://purl.obolibrary.org/obo/DOID_0080745	polymyositis
A hepatic vascular disease that is characterized by a blood clot that forms within the hepatic portal vein. (UMLS CUI:C0155773)	DOID:11695	http://purl.obolibrary.org/obo/DOID_11695	portal vein thrombosis
A constellation of signs and symptoms that can persist for weeks or months after acute infection with SARS-CoV-2, or appear weeks after infection. This condition may be characterized by fatigue, shortness of breath, difficulty focusing or concentrating ("brain fog"), sleep disorders, fevers, gastrointestinal symptoms, anxiety, and depression. aka Long-COVID-19. ACC/AHA Definition:  Symptoms that significantly impair quality of life, which started during or after probable or confirmed acute COVID-19 and have persisted 4 wk to 3 mo after the initial diagnosis of COVID-19	NCIT_C179263	http://purl.obolibrary.org/obo/NCIT_C179263	Post-Acute Sequelae of COVID-19
Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of a solid organ or bone marrow allograft. PTLDs comprise a spectrum ranging from early, Epstein-Barr virus (EBV)-driven polyclonal lymphoid proliferations to EBV-positive or EBV- negative lymphomas of predominantly B-cell or less often T-cell type.	NCIT:C4727	http://purl.obolibrary.org/obo/NCIT_C4727	Post-Transplant Lymphoproliferative Disorder
An anxiety disorder which results from a traumatic experience that results in psychological trauma.	DOID:2055	http://purl.obolibrary.org/obo/DOID_2055	post-traumatic stress disorder
An encephalitis that is characterized by the immune system mistakenly attacking healthy cells in the brain instead of attacking only the cells causing the infection, often occuring two to three weeks after the initial infection.	DOID:10993	http://purl.obolibrary.org/obo/DOID_10993	postinfectious encephalitis
A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.	DOID:10591	http://purl.obolibrary.org/obo/DOID_10591	pre-eclampsia
The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth.	NCIT:C25742	http://purl.obolibrary.org/obo/NCIT_C25742	Pregnancy
Prenatal maternal abnormality	HP:0002686	http://purl.obolibrary.org/obo/HP_0002686	Prenatal maternal abnormality
Birth when a fetus is less than 37 weeks and 0 days gestational age.	NCIT:C92861	http://purl.obolibrary.org/obo/NCIT_C92861	Preterm Birth
Occurring prior to something else.	NCIT:C25627	http://purl.obolibrary.org/obo/NCIT_C25627	Previous
A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.	DOID:12236	http://purl.obolibrary.org/obo/DOID_12236	primary biliary cholangitis
An immune system disease that results when one or more essential parts of the immune system is missing or not working properly at birth due to a genetic mutation.	DOID:612	http://purl.obolibrary.org/obo/DOID_612	primary immunodeficiency disease
A sclerosing cholangitis characterized by fibroobliterative inflammation of the biliary tract, leading to cirrhosis and portal hypertension.	DOID:0060643	http://purl.obolibrary.org/obo/DOID_0060643	primary sclerosing cholangitis
Sjogren syndrome without a concomitant systemic autoimmune disorder.	NCIT:C116985	http://purl.obolibrary.org/obo/NCIT_C116985	Primary Sjogren Syndrome
A rectal disease that involves inflammation of the rectal mucosa, which results from infection, inflammatory bowel disease, or radiation. Sexually transmitted pathogens (Neisseria gonorrhoeae, Chlamydia trachomatis, herpes simplex virus 1 and 2, Treponema pallidum) and enteric pathogens (Campylobacter, Shigella, Salmonella) are involved in the disease. Symptoms are rectal discomfort and bleeding.	DOID:3127	http://purl.obolibrary.org/obo/DOID_3127	proctitis
A skin disease that is characterized by patches of thick red skin and silvery scales.	DOID:8893	http://purl.obolibrary.org/obo/DOID_8893	psoriasis
An arthritis that is characterized by joint inflammation that usually occurs in combination with psoriasis.	DOID:9008	http://purl.obolibrary.org/obo/DOID_9008	psoriatic arthritis
A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. (UMLS CUI:C1658764)	NCIT:C2893	http://purl.obolibrary.org/obo/NCIT_C2893	Psychiatric Disorder
A cognitive disorder that involves abnormal thinking and perceptions resulting in a disconnection with reality.	DOID:2468	http://purl.obolibrary.org/obo/DOID_2468	psychotic disorder
A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.	DOID:6432	http://purl.obolibrary.org/obo/DOID_6432	pulmonary hypertension
pustulosis of palm and sole	DOID:4398	http://purl.obolibrary.org/obo/DOID_4398	pustulosis of palm and sole
Exposure to radioactive materials or ionizing radiation, whether by external irradiation, contact or contamination with radioactive material, or incorporation of radioactive materials, as in the case of certain diagnostic procedures.	NCIT:C61398	http://purl.obolibrary.org/obo/NCIT_C61398	Radiation Exposure
The complex of symptoms characterizing the disease known as radiation injury, resulting from excessive exposure (greater than 200 rads or 2 gray) of the whole body (or large part) to ionizing radiation. The earliest of these symptoms are nausea, fatigue, vomiting, and diarrhea, which may be followed by epilation, hemorrhage, inflammation of the mouth and throat, and general loss of energy. In severe cases, where the radiation exposure has been approximately 1000 Rad (10 gray) or more, death may occur within two to four weeks. Those who survive six weeks after the receipt of a single large dose of radiation to the whole body may generally be expected to recover. (U.S. Nuclear Regulatory Commission).	NCIT:C50723	http://purl.obolibrary.org/obo/NCIT_C50723	Radiation Sickness Syndrome
Raynaud disease	DOID:10300	http://purl.obolibrary.org/obo/DOID_10300	Raynaud disease
A quality of a process which occurs near to or not long before the present.	PATO:0001484	http://purl.obolibrary.org/obo/PATO_0001484	recent
A medical condition characterized by the loss of two or more pregnancies before the fetus reaches viability. The exact timing for what constitutes "viability" may vary, but losses are often counted before 20 weeks of gestation. Recurrent pregnancy loss is a subset of miscarriage, which is more broadly defined as the loss of a pregnancy before viability. Updated term: Abortion, Habitual.	UMLS CUI:C0000809	https://uts.nlm.nih.gov/uts/umls/concept/C0000809	Recurrent pregnancy loss
Repeated infections of the urinary tract. (UMLS CUI:C0262655)	HP:0000010	http://purl.obolibrary.org/obo/HP_0000010	Recurrent urinary tract infections
A disease stage which is preceded by a remission and characterized by the return of a manifestation of a disease.	OGMS:0000105	http://purl.obolibrary.org/obo/OGMS_0000105	relapse
A chondromalacia that is characterized by recurrent inflammation of cartilage and other tissues throughout the body.	DOID:2556	http://purl.obolibrary.org/obo/DOID_2556	relapsing polychondritis
renal artery obstruction	DOID:2972	http://purl.obolibrary.org/obo/DOID_2972	renal artery obstruction
A surgical procedure in the field of reproductive medicine.	NCIT:C157970	http://purl.obolibrary.org/obo/NCIT_C157970	Reproductive Surgery
A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus, which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress.	DOID:1273	http://purl.obolibrary.org/obo/DOID_1273	respiratory syncytial virus infectious disease
A musculoskeletal system disease that involves inflammation or pain in the muscles, joints, or fibrous tissue.	DOID_1575	http://purl.obolibrary.org/obo/DOID_1575	Rheumatic Disease
A heart valve disease that is characterized by repeated inflammation with fibrinous repair caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords.	DOID:0050827	http://purl.obolibrary.org/obo/DOID_0050827	rheumatic heart disease
An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.	DOID:7148	http://purl.obolibrary.org/obo/DOID_7148	rheumatoid arthritis
A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.	DOID:4483	http://purl.obolibrary.org/obo/DOID_4483	rhinitis
An infectious process caused by rhinovirus. The virus usually causes upper respiratory infections, but can infect the lower tract as well.	NCIT:C122572	http://purl.obolibrary.org/obo/NCIT_C122572	Rhinovirus Infection
A viral infectious disease that results_in infection located_in skin, has_material_basis_in Rubella virus, which is transmitted_by droplet spread of oronasal secretions from the infected person through coughing and sneezing, and transmitted_by congenital method. The infection has_symptom rash on the face which spreads to the trunk and limbs, has_symptom fever, has_symptom lymphadenopathy, has_symptom joint pains, has_symptom headache, and has_symptom conjunctivitis.	DOID:8781	http://purl.obolibrary.org/obo/DOID_8781	rubella
A primary bacterial infectious disease caused by the bacteria of the genus Salmonella. It has sypmtoms diarrhea, fever, vomiting, and abdominal cramps 12 to 72 hours after infection. In most cases, the illness lasts four to seven days, and most people recover without treatment.	DOID:0060859	http://purl.obolibrary.org/obo/DOID_0060859	salmonellosis
A hypersensitivity reaction type IV disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs.	DOID:11335	http://purl.obolibrary.org/obo/DOID_11335	sarcoidosis
A cell type cancer that has_material_basis_in abnormally proliferating cells derives from embryonic mesoderm.	DOID:1115	http://purl.obolibrary.org/obo/DOID_1115	sarcoma
A parasitic helminthiasis infectious disease that involves infection of the intestine, urinary tract, skin, liver and spleen caused by multiple species of the trematode fluke of the genus Schistosoma. The symptoms include fever, chills, nausea, abdominal pain, diarrhea, malaise, myalgia, liver and spleen enlargement, rash and hematuria.	DOID:1395	http://purl.obolibrary.org/obo/DOID_1395	schistosomiasis
A rheumatic disease that involves the abnormal growth of connective tissue, which supports the skin and internal organs.	DOID:419	http://purl.obolibrary.org/obo/DOID_419	scleroderma
Allergic rhinitis caused by outdoor allergens.	NCIT:C92188	http://purl.obolibrary.org/obo/NCIT_C92188	Seasonal Allergic Rhinitis
A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in SARS coronavirus (SARS-CoV), which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia	DOID:2945	http://purl.obolibrary.org/obo/DOID_2945	Severe Acute Respiratory Syndrome (SARS)
A COVID-19 that is characterized by any of (1) Oxygen saturation < 90% on room air, (2) Respiratory rate > 30 breaths/min in adults and children > 5 years old, ≥ 60 breaths/min in children < 2 months old, ≥ 50 in children 2–11 months old, and ≥ 40 in children 1–5 years old, or (3) signs of severe respiratory distress (accessory muscle use, inability to complete full sentences, and, in children, very severe chest wall indrawing, grunting, central cyanosis, or presence of any other general danger signs. https://www.who.int/publications/i/item/WHO-2019-nCoV-clinical-2021-1	DOID:0081013	http://purl.obolibrary.org/obo/DOID_0081013	severe COVID-19
A disorder acquired through sexual contact.	NCIT:C3365	http://purl.obolibrary.org/obo/NCIT_C3365	Sexually Transmitted Disorder
An intestinal disease cause by Shigella bacteria.	C157978	http://purl.obolibrary.org/obo/NCIT_C157978	Shigellosis
A dislocation of the shoulder joint. (UMLS CUI:C0037005)	NCIT:C35020	http://purl.obolibrary.org/obo/NCIT_C35020	Shoulder Dislocation
A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape. https://en.wikipedia.org/wiki/Sickle_cell_disease, https://ghr.nlm.nih.gov/condition/sickle-cell-disease, https://www.nhlbi.nih.gov/health-topics/sickle-cell-disease	DOID:10923	https://www.disease-ontology.org/?id=DOID:10923	sickle cell anemia
A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip.	DOID:0050127	http://purl.obolibrary.org/obo/DOID_0050127	sinusitis
An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.	DOID:12894	http://purl.obolibrary.org/obo/DOID_12894	Sjogren's syndrome
Replacing diseased bowel with healthy bowel tissue.	NCIT:C157985	http://purl.obolibrary.org/obo/NCIT_C157985	Small Bowel Transplantation
Smaller than normal size according to sex and gestational age related norms, defined as a weight below the 10th percentile for the gestational age (UMLS CUI: C0235991).	NCIT:C114934	http://purl.obolibrary.org/obo/NCIT_C114934	Small for Gestational Age
A viral infectious disease that results in infection located in skin, has_material_basis_in Variola virus, which is transmitted by droplets from oral, nasal or pharyngeal mucosa, transmitted by contact with the body fluids, or transmitted by fomites. The infection results in formation of lesions, first on the face, hands and forearms and later on the trunk.	DOID:8736	http://purl.obolibrary.org/obo/DOID_8736	smallpox
A benign or malignant neoplasm arising from tissues that do not include fluid areas.  Representative examples include epithelial neoplasms (e.g. lung carcinoma, prostate carcinoma, breast carcinoma, colon carcinoma), and neoplasms arising from the soft tissues and bones (e.g. leiomyosarcoma, liposarcoma, chondrosarcoma, osteosarcoma).  Neoplasms originating from the blood or bone marrow (leukemias and myeloproliferative disorders) are not considered solid tumors.	NCIT:C9292	http://purl.obolibrary.org/obo/NCIT_C9292	Solid Neoplasm
An individual who is receiving a transplant of a solid organ.	NCIT:C130200	http://purl.obolibrary.org/obo/NCIT_C130200	Solid Organ Transplant Recipient
A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination.	DOID:0060038	http://purl.obolibrary.org/obo/DOID_0060038	specific developmental disorder
A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy.	DOID:12377	http://purl.obolibrary.org/obo/DOID_12377	spinal muscular atrophy
Spontaneous abortion is a abortion characterized by the naturally occurring expulsion of a nonviable fetus.	SYMP:0000199	http://purl.obolibrary.org/obo/SYMP_0000199	spontaneous abortion
Preterm birth from 20 weeks to 36 weeks, 6 days of gestation associated with one of the following: classic preterm labor or preterm premature rupture of membranes.	NCIT:C112864	http://purl.obolibrary.org/obo/NCIT_C112864	Spontaneous Preterm Birth
An infectious process in which the bacteria Staphylococcus aureus is present.	NCIT:C122576	http://purl.obolibrary.org/obo/NCIT_C122576	Staphylococcus Aureus Infection
A skin disease that is characterized by ulceration of less than 10 percent of the surface area of the body. The disease is often precipitated by the use of medications, such as antibiotics or antiepileptics, or onset of infection.	DOID:0050426	http://purl.obolibrary.org/obo/DOID_0050426	Stevens-Johnson syndrome
Stillbirth is a reproductive system symptom characterized by the birth of a dead fetus, occurs when a fetus which has died in the uterus or during labor or delivery exits a woman's body.	SYMP:0000849	http://purl.obolibrary.org/obo/SYMP_0000849	stillbirth
Inflammation of the throat due to Streptococcus pyogenes.	NCIT:C116003	http://purl.obolibrary.org/obo/NCIT_C116003	Streptococcal Pharyngitis
A bacterial pneumonia has_material_basis_in Streptococcus pneumoniae.	DOID:0040084	http://purl.obolibrary.org/obo/DOID_0040084	Streptococcus pneumonia
A substance-related disorder that involves a maladaptive pattern of substance use leading to significant impairment in functioning.	DOID:302	http://purl.obolibrary.org/obo/DOID_302	substance abuse
A disease of mental health involving the abuse or dependence on a substance that is ingested in order to produce a high, alter one's senses, or otherwise affect functioning. (UMLS CUI:C0038586)	DOID:303	http://purl.obolibrary.org/obo/DOID_303	substance-related disorder
A skin disease that is characterized by sudden onset of well defined tender plaques or nodules accompanied by fever, arthralgias, ocular inflammation, headaches and, rarely, oral or genital lesions.	DOID:0080746	http://purl.obolibrary.org/obo/DOID_0080746	Sweet syndrome
An influenza that results_in infection located_in respiratory tract of pigs and humans, has_material_basis_in Influenza C virus, or has_material_basis_in Influenza A virus subtypes (H1N1, H1N2, H3N1, H3N2, and H2N3), which are transmitted_by direct contact with infected pigs. The infection in humans has_symptom fever, has_symptom lethargy, has_symptom lack of appetite, has_symptom coughing, has_symptom runny nose, has_symptom sore throat, has_symptom nausea, has_symptom vomiting, and has_symptom diarrhea.	DOID:0050211	http://purl.obolibrary.org/obo/DOID_0050211	swine influenza
A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.	DOID:9074	http://purl.obolibrary.org/obo/DOID_9074	systemic lupus erythematosus
A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.	DOID:418	http://purl.obolibrary.org/obo/DOID_418	systemic scleroderma
A primary bacterial infectious disease that results in prolonged contraction of skeletal muscle fibers, has_material_basis_in Clostridium tetani, which produces tetanospasmin, a neurotoxin, which is carried to the brain and spinal cord, where it binds irreversibly to receptors inhibiting neurotransmission. Damaged upper motor neurons cannot control reflex responses to afferent sensory stimuli.	DOID:11338	http://purl.obolibrary.org/obo/DOID_11338	tetanus
An upper respiratory tract disease which is characterized by inflammation of the tonsils resulting from bacterial (Group A streptococcus) and viral (Epstein-Barr virus, adenovirus) infections. Symptoms include a severe sore throat, painful or difficult swallowing, coughing, headache, myalgia, fever and chills.	DOID:10456	http://purl.obolibrary.org/obo/DOID_10456	tonsillitis
A syndrome that is characterized by congenital infection with toxoplasmosis, rubella, cytomegalovirus, herpes simplex, and other organisms.	DOID:0080835	http://purl.obolibrary.org/obo/DOID_0080835	TORCH syndrome
A myelitis that is characterized by a band-like sensation across the trunk of the body, with sensory changes below.	DOID:0080743	http://purl.obolibrary.org/obo/DOID_0080743	transverse myelitis
A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.	DOID:399	http://purl.obolibrary.org/obo/DOID_399	tuberculosis
A primary bacterial infectious disease that has_material_basis_in Francisella tularensis, which is transmitted by dog tick bite (Dermacentor variabilis), transmitted by deer flies (Chrysops sp) or transmitted by contact with infected animal tissues.	DOID:2123	http://purl.obolibrary.org/obo/DOID_2123	tularemia
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.	DOID:9744	http://purl.obolibrary.org/obo/DOID_9744	type 1 diabetes mellitus
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.	DOID:9352	http://purl.obolibrary.org/obo/DOID_9352	type 2 diabetes mellitus
A primary bacterial infectious disease that is a communicable systemic illness, has_material_basis_in Salmonella enterica subsp enterica serovar Typhi, which is transmitted_by ingestion of food or water contaminated with the feces of an infected person. The infection has_symptom fever, has_symptom diarrhea, has_symptom prostration, has_symptom headache, has_symptom splenomegaly, has_symptom liver enlargement, has_symptom eruption of rose-colored spots, and has_symptom leukopenia.	DOID:13258	http://purl.obolibrary.org/obo/DOID_13258	typhoid fever
A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.	DOID:8577	http://purl.obolibrary.org/obo/DOID_8577	ulcerative colitis
A respiratory system disease which involves the upper respiratory tract.	DOID:974	http://purl.obolibrary.org/obo/DOID_974	upper respiratory tract disease
Urinary tract obstruction is a blockage that inhibits the flow of urine through its normal path (the urinary tract), including the kidneys, ureters, bladder, and urethra. Blockage can be complete or partial. Blockage can lead to kidney damage, kidney stones, and infection.	DOID:5200	http://purl.obolibrary.org/obo/DOID_5200	urinary tract obstruction
An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.	DOID:13141	http://purl.obolibrary.org/obo/DOID_13141	uveitis
A vascular disease that is characterized by inflammation of the blood vessels.	DOID:865	http://purl.obolibrary.org/obo/DOID_865	vasculitis
A respiratory tract infection caused by a virus.  Viruses represent the most common causes of upper and lower respiratory tract infections and include rhinoviruses, influenza viruses, parainfluenza viruses, and respiratory syncytial virus.	NCIT:C27219	http://purl.obolibrary.org/obo/NCIT_C27219	Viral Respiratory Tract Infection
The specificity of a virus for infecting a particular type of cell or tissue.	MESH:D056189	http://id.nlm.nih.gov/mesh/D056189	viral tropism
An autoimmune disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes.	DOID:12306	http://purl.obolibrary.org/obo/DOID_12306	vitiligo
Water-Electrolyte Imbalance	OMIT:0015710	http://purl.obolibrary.org/obo/OMIT_0015710	Water-Electrolyte Imbalance
weight loss	SYMP:0000178	http://purl.obolibrary.org/obo/SYMP_0000178	weight loss
A viral infectious disease that results in inflammation located in brain, has_material_basis_in West Nile virus, which is transmitted_by Culex, transmitted by Aedes, and transmitted_by Anopheles species of mosquitoes. The infection has_symptom high fever, has_symptom headache, has_symptom neck stiffness, has_symptom stupor, has_symptom disorientation, has_symptom coma, has_symptom tremors, has_symptom convulsions, has_symptom muscle weakness, has_symptom vision loss, has_symptom numbness, and has_symptom paralysis.	DOID:2365	http://purl.obolibrary.org/obo/DOID_2365	West Nile encephalitis
A viral infectious disease that results_in infection, has_material_basis_in West Nile virus, which is transmitted_by Culex and transmitted_by Aedes mosquitoes. The infection has_symptom fever, has_symptom sore throat, has_symptom headache, has_symptom body ache, has_symptom nausea, has_symptom maculopapular rash and has_symptom vomiting.	DOID:2366	http://purl.obolibrary.org/obo/DOID_2366	West Nile fever
An immunodeficiency state characterized (usually) by profoundly low concentrations of serum immunoglobulins of all classes, although occasionally significant amounts of one or more isotypes can be found. The fundamental defect in XLA affects early lineage B cells	NCIT_C3822	http://purl.obolibrary.org/obo/NCIT_C3822	X-linked agammaglobulinemia
A viral infectious disease that results in infection, has_material_basis_in Yellow fever virus, which is transmitted by Aedes, transmitted by Haemagogus, or transmitted by Sabethes species of mosquitoes. The infection has symptom fever, has symptom muscle pain, has symptom backache, has symptom headache, has symptom shivers, has symptom loss of appetite, has symptom jaundice, and has symptom bleeding from the mouth, nose, eyes or stomach leading to vomitus containing blood.	DOID:9682	http://purl.obolibrary.org/obo/DOID_9682	yellow fever
A viral infectious disease that has_material_basis in Zika virus, which is transmitted_by Aedes aegypti mosquitoes and targets neural progenitor cells and  neuronal cells in all stages of maturity and has_symptom fever, has_symptom rash, has_symptom headaches and has_symptom joint pain.	DOID:0060478	http://purl.obolibrary.org/obo/DOID_0060478	Zika fever